Science

Science

At IOVE, we translate rigorous research in cellular defence into elegant, daily routines. Our formulations are grounded in peer-reviewed biology and verified quality—so you can act on the science with confidence.

The Science behind Pteroyouth

A Breakthrough in Cellular Resilience

Our patented Pteroyouth complex combines advanced bioactive ingredients proven to protect, regenerate, and optimize cellular health for longevity and vitality.

A Breakthrough in Cellular Resilience

How it works

As we age, our cells lose efficiency. Stress, toxins, and inflammation speed up this decline. Origin helps your body fight back by activating key cellular pathways linked to longevity and repair.

How it works

Pteroyouth activates SIRT1 and SIRT3

Sirtuins are proteins that help repair DNA, reduce inflammation, and support energy production. They’re considered “longevity regulators”.

Pteroyouth activates SIRT1 and SIRT3

Why Sirtuins Matter

Sirtuins (especially SIRT1 and SIRT3) are enzymes that play a crucial role in cellular health, longevity, and resilience. Activating them can help protect cells from aging and stress-related damage. ORIGIN, powered by Pteroyouth stands out as a superior activator of sirtuins, which may translate into better support for cellular health and longevity. Its enhanced bioavailability makes it more effective than both resveratrol and standard pterostilbene in all tested cell types (lymphocytes, liver cells, and intestinal cells).

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Pteroyouth boosts NAD+ levels

NAD⁺ is a molecule your cells need to produce energy and activate sirtuins. It naturally declines with age.

Pteroyouth boosts NAD+ levels

Why NAD+ is important

NAD⁺ (nicotinamide adenine dinucleotide) is a vital molecule found in every cell of the body. It helps:

Produce energy

Repair DNA

Protect cells from stress

Support healthy aging

As we age, NAD⁺ levels naturally decline, which can lead to fatigue, slower recovery, and reduced cellular resilience.

Why this matters for ORIGIN

ORIGIN contains a NAD⁺ booster based. This means:

It helps replenish NAD⁺ levels that decline with age or stress.

It supports cellular energy, repair, and resilience.

It may contribute to better overall health and longevity

In Summary

Taking ORIGIN can help your body maintain healthy NAD⁺ levels, which are essential for energy, repair, and aging well. The study confirms that NR supplementation works effectively in vivo — making ORIGIN a scientifically backed choice for supporting cellular health.

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Pteroyouth improves cellular defense through the activation of Nrf2 factor helps balance inflammation by influencing NF-κB

Nrf2 is a protein that tells your body to produce its own antioxidants — your natural defense against stress and aging. NF-κB is a key regulator of the immune response.

Pteroyouth improves cellular defense through the activation of Nrf2 factor helps balance inflammation by influencing NF-κB

How ORIGIN Helps Your Cells Defend, Repair, and Stay Balanced

ORIGIN combines advanced polyphenols and a NAD⁺ booster to activate key cellular pathways that protect and rejuvenate your cells. One of the most important is NRF2, a master switch that turns on your body’s natural antioxidant defenses. When activated, NRF2 increases the production of protective enzymes like:

SOD1 & SOD2 – neutralize harmful free radicals.

GPX2 & TXNRD1 – detoxify and reduce oxidative stress.

SIRT1 & SIRT3 – support DNA repair and cellular longevity.

PARP1 – helps fix damaged DNA.

These enzymes were more than doubled in treated cells, showing strong antioxidant and DNA-repair effects. At the same time, ORIGIN helps balance inflammation by influencing NF-κB, a key regulator of the immune response. While NF-κB is essential for fighting infections, overactivation can lead to chronic inflammation. ORIGIN helps keep NF-κB in check, promoting a healthier inflammatory balance.

In Summary

ORIGIN activates NRF2, balances NF-κB, and boosts NAD⁺ to help your cells:

Fight stress

Repair damage

Control inflammation

Age more gracefully

It’s a science-backed formula designed to support long-term cellular health and resilience.

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Pteroyouth supports your cells’ ability to stay clean, efficient, and strong.

Autophagy is your body’s way of cleaning out damaged cells and renewing them. It’s essential for long-term health.

Pteroyouth supports your cells’ ability to stay clean, efficient, and strong.

What Is Autophagy and Why It Matters

Autophagy is a natural process where cells clean up and recycle their damaged or unnecessary parts. Think of it as the cell’s internal housekeeping system — helping to remove waste, repair damage, and stay healthy.

During autophagy, cells form small bubbles called autophagosomes that capture unwanted material. These then merge with lysosomes, which break everything down so the cell can reuse the components.

Cells treated with ORIGIN’s Pteroyouth showed increased autophagy activity, helping them better cope with stress and damage. This was visible as stronger green signals in the image, indicating more active recycling. Lorem ipsum dolor sit amet, consectetur adipiscing elit.

Why it’s important

Autophagy:

Protect cells from stress

Prevent buildup of toxic materials

Support longevity and resilience

By promoting autophagy, ORIGIN supports your cells’ ability to stay clean, efficient, and strong — especially under challenging conditions. Lorem ipsum dolor sit amet, consectetur adipiscing elit.

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Proven cellular defense

Unlike other supplements that only improve biomarkers, Origin has shown real cellular protection in high-stress models. Cells supported by Origin survived and recovered better — a clear sign of true biological impact. This is not just theory. It’s proven cellular resilience. The formulation mitigates oxidative damage, enhances DNA repair, and promotes recovery across multiple organ systems through Nrf2 activation, NF-kB suppression, cell death inhibition and autophagy induction.

Proven cellular defense